A Consortium led by AptaTargets has been awarded with public funding from the RETOS program for exploring new indications for ApTOLL, a DNA aptamer targeting TLR4 with an anti-inflammatory effect. The Consortium RETOS-SafeTOLL (RTC-2017-6283-1) is also composed by the Neurovascular Research Unit (Complutense University, Madrid) and the Institute of Biomedical Research (UAM-CSIC, Madrid) and has a total budget of 503,800 EU.

AptaTargets is the leader of the NeuroToll project, aiming to the clinical development of ApTOLL, an innovative neuroprotective drug for the acute treatment of stroke. The project focuses in stroke program, advancing from late preclinical phase and up to clinical trials Phase II in stroke patients. The project has obtained funding from the Ministry of Science, Innovation and Universities through the RETOS-COLABORACION program, which includes FEDER funding (RTC-2017-6651-1). The consortium is formed by AptaTargets along with several hospitals of reference in the stroke field, such as Germans Trias i Pujol (HGTiP, Barcelona), La Princesa (HULP, Madrid), Virgen del Rocio and Macarena (FISEVI, Sevilla). The project has an aggregated budget of around 3.1 M EU.

(Comunidad de Madrid).

The project involves a doctoral program aiming the study of further application of ApTOLL in Multiple Sclerosis.

AptaTargets has been awarded with the Headstart Program.

The Spanish Centre for the Development of Industrial Technology (CDTI) has granted AptaTargets with funds from the Neotec Program. AptaTargets aims to advance in the pre-clinical and clinical development of ApToll (a molecule based on aptamer technology and targeting inflammation) in acute ischemic stroke and other indications (myocardial infarction and Multiple Sclerosis).

‘la Caixa’, throught their venture capital arm Caixa Capital Risc, and Inveready have invested €2.7 million in AptaTargets, which will allow this biopharmaceutical company to complete the preclinical phase and move into phase I and II clinical trials on its first drug candidate (ApTOLL) to treat acute ischemic stroke. Press release

The Spanish Centre for the Development of Industrial Technology (CDTI) has granted AptaTargets with funds from the Neotec Program. AptaTargets aims to advance in the pre-clinical and clinical development of ApToll (a molecule based on aptamer technology and targeting inflammation) in acute ischemic stroke and other indications (myocardial infarction and Multiple Sclerosis).